The Fanconi Anemia Pathway Limits Human Papillomavirus Replication

High-risk human papillomaviruses (HPVs) deregulate epidermal differentiation and cause anogenital and head and neck squamous cell carcinomas (SCCs). The E7 gene is considered the predominant viral oncogene and drives proliferation and genome instability. While the implementation of routine screens h...

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Detalhes bibliográficos
Main Authors: Hoskins, Elizabeth E., Morreale, Richard J., Werner, Stephen P., Higginbotham, Jennifer M., Laimins, Laimonis A., Lambert, Paul F., Brown, Darron R., Gillison, Maura L., Nuovo, Gerard J., Witte, David P., Kim, Mi-Ok, Davies, Stella M., Mehta, Parinda A., Butsch Kovacic, Melinda, Wikenheiser-Brokamp, Kathryn A., Wells, Susanne I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Transformation and Oncogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421690/
https://ncbi.nlm.nih.gov/pubmed/22623785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00408-12
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