The Fanconi Anemia Pathway Limits Human Papillomavirus Replication

High-risk human papillomaviruses (HPVs) deregulate epidermal differentiation and cause anogenital and head and neck squamous cell carcinomas (SCCs). The E7 gene is considered the predominant viral oncogene and drives proliferation and genome instability. While the implementation of routine screens h...

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Détails bibliographiques
Auteurs principaux: Hoskins, Elizabeth E., Morreale, Richard J., Werner, Stephen P., Higginbotham, Jennifer M., Laimins, Laimonis A., Lambert, Paul F., Brown, Darron R., Gillison, Maura L., Nuovo, Gerard J., Witte, David P., Kim, Mi-Ok, Davies, Stella M., Mehta, Parinda A., Butsch Kovacic, Melinda, Wikenheiser-Brokamp, Kathryn A., Wells, Susanne I.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
Sujets:
Transformation and Oncogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421690/
https://ncbi.nlm.nih.gov/pubmed/22623785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00408-12
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