The Fanconi Anemia Pathway Limits Human Papillomavirus Replication

High-risk human papillomaviruses (HPVs) deregulate epidermal differentiation and cause anogenital and head and neck squamous cell carcinomas (SCCs). The E7 gene is considered the predominant viral oncogene and drives proliferation and genome instability. While the implementation of routine screens h...

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Hlavní autoři: Hoskins, Elizabeth E., Morreale, Richard J., Werner, Stephen P., Higginbotham, Jennifer M., Laimins, Laimonis A., Lambert, Paul F., Brown, Darron R., Gillison, Maura L., Nuovo, Gerard J., Witte, David P., Kim, Mi-Ok, Davies, Stella M., Mehta, Parinda A., Butsch Kovacic, Melinda, Wikenheiser-Brokamp, Kathryn A., Wells, Susanne I.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2012
Témata:
Transformation and Oncogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3421690/
https://ncbi.nlm.nih.gov/pubmed/22623785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00408-12
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