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Prion Strain- and Species-Dependent Effects of Antiprion Molecules in Primary Neuronal Cultures
Transmissible spongiform encephalopathies (TSE) arise as a consequence of infection of the central nervous system by prions and are incurable. To date, most antiprion compounds identified by in vitro screening failed to exhibit therapeutic activity in animals, thus calling for new assays that could...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2007
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2168876/ https://ncbi.nlm.nih.gov/pubmed/17913812 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01502-07 |
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