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Prion Strain- and Species-Dependent Effects of Antiprion Molecules in Primary Neuronal Cultures

Transmissible spongiform encephalopathies (TSE) arise as a consequence of infection of the central nervous system by prions and are incurable. To date, most antiprion compounds identified by in vitro screening failed to exhibit therapeutic activity in animals, thus calling for new assays that could...

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Hlavní autoři: Cronier, Sabrina, Beringue, Vincent, Bellon, Anne, Peyrin, Jean-Michel, Laude, Hubert
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2168876/
https://ncbi.nlm.nih.gov/pubmed/17913812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01502-07
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