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Prions can infect primary cultured neurons and astrocytes and promote neuronal cell death

Transmissible spongiform encephalopathies arise as a consequence of infection of the central nervous system by prions, where neurons and glial cells are regarded as primary targets. Neuronal loss and gliosis, associated with the accumulation of misfolded prion protein (PrP), are hallmarks of prion d...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Cronier, Sabrina, Laude, Hubert, Peyrin, Jean-Michel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514468/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15302929/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0402725101
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