To develop with or without the prion protein

The deletion of the cellular form of the prion protein (PrP(C)) in mouse, goat, and cattle has no drastic phenotypic consequence. This stands in apparent contradiction with PrP(C) quasi-ubiquitous expression and conserved primary and tertiary structures in mammals, and its pivotal role in neurodegen...

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Detalhes bibliográficos
Main Authors: Halliez, Sophie, Passet, Bruno, Martin-Lannerée, Séverine, Hernandez-Rapp, Julia, Laude, Hubert, Mouillet-Richard, Sophie, Vilotte, Jean-Luc, Béringue, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207017/
https://ncbi.nlm.nih.gov/pubmed/25364763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00058
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