To develop with or without the prion protein

The deletion of the cellular form of the prion protein (PrP(C)) in mouse, goat, and cattle has no drastic phenotypic consequence. This stands in apparent contradiction with PrP(C) quasi-ubiquitous expression and conserved primary and tertiary structures in mammals, and its pivotal role in neurodegen...

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Bibliographic Details
Main Authors: Halliez, Sophie, Passet, Bruno, Martin-Lannerée, Séverine, Hernandez-Rapp, Julia, Laude, Hubert, Mouillet-Richard, Sophie, Vilotte, Jean-Luc, Béringue, Vincent
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2014
Subjects:
Cell and Developmental Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207017/
https://ncbi.nlm.nih.gov/pubmed/25364763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00058
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