To develop with or without the prion protein

The deletion of the cellular form of the prion protein (PrP(C)) in mouse, goat, and cattle has no drastic phenotypic consequence. This stands in apparent contradiction with PrP(C) quasi-ubiquitous expression and conserved primary and tertiary structures in mammals, and its pivotal role in neurodegen...

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Hlavní autoři: Halliez, Sophie, Passet, Bruno, Martin-Lannerée, Séverine, Hernandez-Rapp, Julia, Laude, Hubert, Mouillet-Richard, Sophie, Vilotte, Jean-Luc, Béringue, Vincent
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2014
Témata:
Cell and Developmental Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207017/
https://ncbi.nlm.nih.gov/pubmed/25364763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2014.00058
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