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Characterization of covalent Adriamycin-DNA adducts

Adriamycin is a popular antineoplastic agent whose ability to form covalent adducts with DNA has been correlated to cellular apoptosis (programmed cell death) in tumor models. We have isolated and purified this adduct formed under oxido-reductive (Fenton) conditions in Tris buffer. We show by homo-...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Zeman, Steven M., Phillips, Don R., Crothers, Donald M.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 1998
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC21680/
https://ncbi.nlm.nih.gov/pubmed/9751705
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