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In Vitro Resistance Study of Rupintrivir, a Novel Inhibitor of Human Rhinovirus 3C Protease

Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease. The potential for res...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Binford, S. L., Weady, P. T., Maldonado, F., Brothers, M. A., Matthews, D. A., Patick, A. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167992/
https://ncbi.nlm.nih.gov/pubmed/17908951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00905-07
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