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In Vitro Resistance Study of Rupintrivir, a Novel Inhibitor of Human Rhinovirus 3C Protease

Rupintrivir (formerly AG7088) is an irreversible inhibitor of the human rhinovirus (HRV) 3C protease that has been demonstrated to have in vitro activity against all HRVs tested, consistent with its interaction with a strictly conserved subset of amino acids in the 3C protease. The potential for res...

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Hlavní autoři: Binford, S. L., Weady, P. T., Maldonado, F., Brothers, M. A., Matthews, D. A., Patick, A. K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2167992/
https://ncbi.nlm.nih.gov/pubmed/17908951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00905-07
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