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Replacement of Iγ3 germ-line promoter by Iγ1 inhibits class-switch recombination to IgG3

Class-switch recombination (CSR) enables IgM-producing B cells to switch to the production of IgG, IgE, and IgA. The process requires germ-line (GL) transcription that initiates from promoters upstream of switch (S) sequences and is regulated by the 3′ regulatory region (3′RR) located downstream of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Oruc, Zeliha, Boumédiène, Ahmed, Le Bert, Marc, Khamlichi, Ahmed Amine
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2154457/
https://ncbi.nlm.nih.gov/pubmed/18077389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608364104
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