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Replacement of Iγ3 germ-line promoter by Iγ1 inhibits class-switch recombination to IgG3
Class-switch recombination (CSR) enables IgM-producing B cells to switch to the production of IgG, IgE, and IgA. The process requires germ-line (GL) transcription that initiates from promoters upstream of switch (S) sequences and is regulated by the 3′ regulatory region (3′RR) located downstream of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2154457/ https://ncbi.nlm.nih.gov/pubmed/18077389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608364104 |
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