Molecular Determinants of PI(4,5)P(2) and PI(3,4,5)P(3) Regulation of the Epithelial Na(+) Channel

Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) and phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P(3)) are physiologically important second messengers. These molecules bind effector proteins to modulate activity. Several types of ion channels, including the epithelial Na(+) channel (ENaC),...

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Detalhes bibliográficos
Main Authors: Pochynyuk, Oleh, Tong, Qiusheng, Medina, Jorge, Vandewalle, Alain, Staruschenko, Alexander, Bugaj, Vladislav, Stockand, James D.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2151653/
https://ncbi.nlm.nih.gov/pubmed/17893193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200709800
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