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Binding and direct activation of the epithelial Na(+) channel (ENaC) by phosphatidylinositides

Several distinct types of ion channels bind and directly respond to phosphatidylinositides, including phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P(3)) and phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P(2)). This regulation is physiologically relevant for its dysfunction, in some instanc...

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Detalhes bibliográficos
Main Authors: Pochynyuk, Oleh, Tong, Qiusheng, Staruschenko, Alexander, Stockand, James D
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2075560/
https://ncbi.nlm.nih.gov/pubmed/17272344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.127449
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