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Physiologic regulation of the epithelial Na(+) channel (ENaC) by phosphatidylinositides

PURPOSE OF REVIEW: Epithelial Na(+) channel (ENaC) activity is limiting for Na(+) reabsorption in the distal nephron. Humans regulate blood pressure by fine-tuning Na(+) balance through control of ENaC. ENaC dysfunction is causative for some hypertensive and renal salt wasting diseases. Thus, it is...

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Main Authors: Pochynyuk, Oleh, Bugaj, Vladislav, Stockand, James D.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655798/
https://ncbi.nlm.nih.gov/pubmed/18695396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0b013e328308fff3
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