Purinergic Inhibition of ENaC Produces Aldosterone Escape

The mechanisms underlying “aldosterone escape,” which refers to the excretion of sodium (Na(+)) during high Na(+) intake despite inappropriately increased levels of mineralocorticoids, are incompletely understood. Because local purinergic tone in the aldosterone-sensitive distal nephron downregulate...

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Hlavní autoři: Stockand, James D., Mironova, Elena, Bugaj, Vladislav, Rieg, Timo, Insel, Paul A., Vallon, Volker, Peti-Peterdi, Janos, Pochynyuk, Oleh
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Nephrology 2010
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014005/
https://ncbi.nlm.nih.gov/pubmed/20813869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010040377
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