PI(3,4,5)P(3) and PI(4,5)P(2) Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane

Many signaling, cytoskeletal, and transport proteins have to be localized to the plasma membrane (PM) in order to carry out their function. We surveyed PM-targeting mechanisms by imaging the subcellular localization of 125 fluorescent protein–conjugated Ras, Rab, Arf, and Rho proteins. Out of 48 pro...

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Detalhes bibliográficos
Main Authors: Heo, Won Do, Inoue, Takanari, Park, Wei Sun, Kim, Man Lyang, Park, Byung Ouk, Wandless, Thomas J., Meyer, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579512/
https://ncbi.nlm.nih.gov/pubmed/17095657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1134389
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