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PI(3,4,5)P(3) and PI(4,5)P(2) Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane

Many signaling, cytoskeletal, and transport proteins have to be localized to the plasma membrane (PM) in order to carry out their function. We surveyed PM-targeting mechanisms by imaging the subcellular localization of 125 fluorescent protein–conjugated Ras, Rab, Arf, and Rho proteins. Out of 48 pro...

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Bibliografische gegevens
Hoofdauteurs: Heo, Won Do, Inoue, Takanari, Park, Wei Sun, Kim, Man Lyang, Park, Byung Ouk, Wandless, Thomas J., Meyer, Tobias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579512/
https://ncbi.nlm.nih.gov/pubmed/17095657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1134389
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