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PI(3,4,5)P(3) and PI(4,5)P(2) Lipids Target Proteins with Polybasic Clusters to the Plasma Membrane
Many signaling, cytoskeletal, and transport proteins have to be localized to the plasma membrane (PM) in order to carry out their function. We surveyed PM-targeting mechanisms by imaging the subcellular localization of 125 fluorescent protein–conjugated Ras, Rab, Arf, and Rho proteins. Out of 48 pro...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3579512/ https://ncbi.nlm.nih.gov/pubmed/17095657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1134389 |
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