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PI(3,4,5)P(3) Potentiates Phospholipase C-β Activity
Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Previously, we had shown that PLC-β1 and PLC-β3 bound immobilized PIP(3). In this study, PIP(3) was found to potentiate Ca(2+)-stimulated PLC-β activities using an in vitro reconstitution assay. LY294002, a...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2830898/ https://ncbi.nlm.nih.gov/pubmed/19519170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10799890902729449 |
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