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Localizing frustration in native proteins and protein assemblies
We propose a method of quantifying the degree of frustration manifested by spatially local interactions in protein biomolecules. This method of localization smoothly generalizes the global criterion for an energy landscape to be funneled to the native state, which is in keeping with the principle of...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2148382/ https://ncbi.nlm.nih.gov/pubmed/18077414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709915104 |
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