Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP

cAMP is well known to regulate exocytosis in various secretory cells, but the precise mechanism of its action remains unknown. Here, we examine the role of cAMP signaling in the exocytotic process of insulin granules in pancreatic beta cells. Although activation of cAMP signaling alone does not caus...

詳細記述

保存先:
書誌詳細
主要な著者: Shibasaki, Tadao, Takahashi, Harumi, Miki, Takashi, Sunaga, Yasuhiro, Matsumura, Kimio, Yamanaka, Mami, Zhang, Changliang, Tamamoto, Atsuko, Satoh, Takaya, Miyazaki, Jun-ichi, Seino, Susumu
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148290/
https://ncbi.nlm.nih.gov/pubmed/18040047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707054104
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