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Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1
Exchange protein directly activated by cAMP-1 (Epac1) is a cAMP sensor that regulates multiple cellular functions including cellular migration, proliferation and differentiation. Classically, Epac1 is thought to exert its effects through binding of cAMP leading to a conformational change in Epac1 an...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5093460/ https://ncbi.nlm.nih.gov/pubmed/27808165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36370 |
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