β‐Cell glutamate signaling: Its role in incretin‐induced insulin secretion

Por Yokoi, Norihide, Gheni, Ghupurjan, Takahashi, Harumi, Seino, Susumu
Publicado no J Diabetes Investig (2016)

Liraglutide Improves Pancreatic Beta Cell Mass and Function in Alloxan-Induced Diabetic Mice

Por Tamura, Kanako, Minami, Kohtaro, Kudo, Maya, Iemoto, Keisuke, Takahashi, Harumi, Seino, Susumu
Publicado no PLoS One (2015)

A Case of Diffuse Alveolar Hemorrhage Associated with Tegafur Plus Uracil and Warfarin Therapy

Por Itoh, Masayuki, Oh-ishi, Shuji, Nemoto, Kenji, Senba, Seitaro, Adachi, Hideki, Kishi, Koji, Nakamura, Hiroyuki, Takahashi, Harumi
Publicado em 2011

Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion

Por Murao, Naoya, Yokoi, Norihide, Honda, Kohei, Han, Guirong, Hayami, Tomohide, Gheni, Ghupurjan, Takahashi, Harumi, Minami, Kohtaro, Seino, Susumu
Publicado no PLoS One (2017)

Actin Dynamics Regulated by the Balance of Neuronal Wiskott-Aldrich Syndrome Protein (N-WASP) and Cofilin Activities Determines the Biphasic Response of Glucose-induced Insulin Sec...

Por Uenishi, Eita, Shibasaki, Tadao, Takahashi, Harumi, Seki, Chihiro, Hamaguchi, Hitomi, Yasuda, Takao, Tatebe, Masao, Oiso, Yutaka, Takenawa, Tadaomi, Seino, Susumu
Publicado em 2013

Decreased Warfarin Clearance with the CYP2C9 R150H (*8) Polymorphism

Por Liu, Yong, Jeong, Hyun-Young, Takahashi, Harumi, Drozda, Katarzyna, Patel, Shitalben R., Shapiro, Nancy L., Nutescu, Edith A., Cavallari, Larisa H.
Publicado em 2012

CYP2C9 promoter region single-nucleotide polymorphisms linked to the R150H polymorphism are functional suggesting their role in CYP2C9*8-mediated effects

Por Cavallari, Larisa H., Vaynshteyn, David, Freeman, Kimberly M., Wang, Danxin, Perera, Minoli A., Takahashi, Harumi, Drozda, Katrzyna, Patel, Shitalben R., Jeong, Hyunyoung
Publicado em 2013

A Novel Diphenylthiosemicarbazide Is a Potential Insulin Secretagogue for Anti-Diabetic Agent

Por Sugawara, Kenji, Honda, Kohei, Reien, Yoshie, Yokoi, Norihide, Seki, Chihiro, Takahashi, Harumi, Minami, Kohtaro, Mori, Ichiro, Matsumoto, Akio, Nakaya, Haruaki, Seino, Susumu
Publicado no PLoS One (2016)

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP

Por Shibasaki, Tadao, Takahashi, Harumi, Miki, Takashi, Sunaga, Yasuhiro, Matsumura, Kimio, Yamanaka, Mami, Zhang, Changliang, Tamamoto, Atsuko, Satoh, Takaya, Miyazaki, Jun-ichi, Seino, Susumu
Publicado em 2007

Determinants of the Over-Anticoagulation Response during Warfarin Initiation Therapy in Asian Patients Based on Population Pharmacokinetic-Pharmacodynamic Analyses

Por Ohara, Minami, Takahashi, Harumi, Lee, Ming Ta Michael, Wen, Ming-Shien, Lee, Tsong-Hai, Chuang, Hui-Ping, Luo, Chen-Hui, Arima, Aki, Onozuka, Akiko, Nagai, Rui, Shiomi, Mari, Mihara, Kiyoshi, Morita, Takashi, Chen, Yuan-Tsong
Publicado em 2014

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

Por Gheni, Ghupurjan, Ogura, Masahito, Iwasaki, Masahiro, Yokoi, Norihide, Minami, Kohtaro, Nakayama, Yasumune, Harada, Kazuo, Hastoy, Benoit, Wu, Xichen, Takahashi, Harumi, Kimura, Kazushi, Matsubara, Toshiya, Hoshikawa, Ritsuko, Hatano, Naoya, Sugawara, Kenji, Shibasaki, Tadao, Inagaki, Nobuya, Bamba, Takeshi, Mizoguchi, Akira, Fukusaki, Eiichiro, Rorsman, Patrik, Seino, Susumu
Publicado no Cell Rep (2014)

Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study

Por Perera, Minoli A, Cavallari, Larisa H, Limdi, Nita A, Gamazon, Eric R, Konkashbaev, Anuar, Daneshjou, Roxana, Pluzhnikov, Anna, Crawford, Dana C, Wang, Jelai, Liu, Nianjun, Tatonetti, Nicholas, Bourgeois, Stephane, Takahashi, Harumi, Bradford, Yukiko, Burkley, Benjamin M, Desnick, Robert J, Halperin, Jonathan L, Khalifa, Sherief I, Langaee, Taimour Y, Lubitz, Steven A, Nutescu, Edith A, Oetjens, Matthew, Shahin, Mohamed H, Patel, Shitalben R, Sagreiya, Hersh, Tector, Matthew, Weck, Karen E, Rieder, Mark J, Scott, Stuart A, Wu, Alan HB, Burmester, James K, Wadelius, Mia, Deloukas, Panos, Wagner, Michael J, Mushiroda, Taisei, Kubo, Michiaki, Roden, Dan M, Cox, Nancy J, Altman, Russ B, Klein, Teri E, Nakamura, Yusuke, Johnson, Julie A
Publicado em 2013