Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP

cAMP is well known to regulate exocytosis in various secretory cells, but the precise mechanism of its action remains unknown. Here, we examine the role of cAMP signaling in the exocytotic process of insulin granules in pancreatic beta cells. Although activation of cAMP signaling alone does not caus...

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Detaylı Bibliyografya
Asıl Yazarlar: Shibasaki, Tadao, Takahashi, Harumi, Miki, Takashi, Sunaga, Yasuhiro, Matsumura, Kimio, Yamanaka, Mami, Zhang, Changliang, Tamamoto, Atsuko, Satoh, Takaya, Miyazaki, Jun-ichi, Seino, Susumu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2148290/
https://ncbi.nlm.nih.gov/pubmed/18040047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0707054104
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