EGF-induced PIP(2) hydrolysis releases and activates cofilin locally in carcinoma cells

Lamellipodial protrusion and directional migration of carcinoma cells towards chemoattractants, such as epidermal growth factor (EGF), depend upon the spatial and temporal regulation of actin cytoskeleton by actin-binding proteins (ABPs). It is generally hypothesized that the activity of many ABPs a...

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Autores principales: van Rheenen, Jacco, Song, Xiaoyan, van Roosmalen, Wies, Cammer, Michael, Chen, Xiaoming, DesMarais, Vera, Yip, Shu-Chin, Backer, Jonathan M., Eddy, Robert J., Condeelis, John S.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2007
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140025/
https://ncbi.nlm.nih.gov/pubmed/18086920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706206
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