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Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

The epidermal growth factor (EGF)–induced increase in free barbed ends, resulting in actin polymerization at the leading edge of the lamellipodium in carcinoma cells, occurs as two transients: an early one at 1 min and a late one at 3 min. Our results reveal that phospholipase (PLC) is required for...

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Detalhes bibliográficos
Main Authors: Mouneimne, Ghassan, Soon, Lilian, DesMarais, Vera, Sidani, Mazen, Song, Xiaoyan, Yip, Shu-Chin, Ghosh, Mousumi, Eddy, Robert, Backer, Jonathan M., Condeelis, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172433/
https://ncbi.nlm.nih.gov/pubmed/15337778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405156
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