Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

The epidermal growth factor (EGF)–induced increase in free barbed ends, resulting in actin polymerization at the leading edge of the lamellipodium in carcinoma cells, occurs as two transients: an early one at 1 min and a late one at 3 min. Our results reveal that phospholipase (PLC) is required for...

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Bibliografiske detaljer
Main Authors: Mouneimne, Ghassan, Soon, Lilian, DesMarais, Vera, Sidani, Mazen, Song, Xiaoyan, Yip, Shu-Chin, Ghosh, Mousumi, Eddy, Robert, Backer, Jonathan M., Condeelis, John
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172433/
https://ncbi.nlm.nih.gov/pubmed/15337778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200405156
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