Cofilin determines the migration behavior and turning frequency of metastatic cancer cells

We have investigated the effects of inhibiting the expression of cofilin to understand its role in protrusion dynamics in metastatic tumor cells, in particular. We show that the suppression of cofilin expression in MTLn3 cells (an apolar randomly moving amoeboid metastatic tumor cell) caused them to...

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Détails bibliographiques
Auteurs principaux: Sidani, Mazen, Wessels, Deborah, Mouneimne, Ghassan, Ghosh, Mousumi, Goswami, Sumanta, Sarmiento, Corina, Wang, Weigang, Kuhl, Spencer, El-Sibai, Mirvat, Backer, Jonathan M., Eddy, Robert, Soll, David, Condeelis, John
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2007
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080932/
https://ncbi.nlm.nih.gov/pubmed/18025308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707009
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