Cofilin determines the migration behavior and turning frequency of metastatic cancer cells

We have investigated the effects of inhibiting the expression of cofilin to understand its role in protrusion dynamics in metastatic tumor cells, in particular. We show that the suppression of cofilin expression in MTLn3 cells (an apolar randomly moving amoeboid metastatic tumor cell) caused them to...

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Detalhes bibliográficos
Main Authors: Sidani, Mazen, Wessels, Deborah, Mouneimne, Ghassan, Ghosh, Mousumi, Goswami, Sumanta, Sarmiento, Corina, Wang, Weigang, Kuhl, Spencer, El-Sibai, Mirvat, Backer, Jonathan M., Eddy, Robert, Soll, David, Condeelis, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2080932/
https://ncbi.nlm.nih.gov/pubmed/18025308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707009
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