WASP family members and formin proteins coordinate regulation of cell protrusions in carcinoma cells

We examined the role of the actin nucleation promoters neural Wiskott-Aldrich syndrome protein (N-WASP) and WAVE2 in cell protrusion in response to epidermal growth factor (EGF), a key regulator in carcinoma cell invasion. We found that WAVE2 knockdown (KD) suppresses lamellipod formation and increa...

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Detalhes bibliográficos
Main Authors: Sarmiento, Corina, Wang, Weigang, Dovas, Athanassios, Yamaguchi, Hideki, Sidani, Mazen, El-Sibai, Mirvat, DesMarais, Vera, Holman, Holly A., Kitchen, Susan, Backer, Jonathan M., Alberts, Art, Condeelis, John
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290849/
https://ncbi.nlm.nih.gov/pubmed/18362183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200708123
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