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Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension

Both the Arp2/3 complex and cofilin are believed to be important for the generation of protrusive force at the leading edge; however, their relative contributions have not been explored in vivo. Our results with living cells show that cofilin enters the leading edge immediately before the start of l...

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Autori principali: DesMarais, Vera, Macaluso, Frank, Condeelis, John, Bailly, Maryse
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351153/
https://ncbi.nlm.nih.gov/pubmed/15252126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.01211
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