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Arp2/3 complex-mediated actin polymerisation occurs on specific pre-existing networks in cells and requires spatial restriction to sustain functional lamellipod extension

The classical Arp2/3-mediated dendritic network defines the cytoskeleton at the leading edge of crawling cells, and it is generally assumed that Arp2/3-mediated actin polymerization generates the force necessary to extend lamellipods. Our previous work suggested that successful lamellipod extension...

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Detalhes bibliográficos
Publicado no:Cell Motil Cytoskeleton
Main Authors: Shao, D, Forge, A, Munro, P.M.G, Bailly, M
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7611918/
https://ncbi.nlm.nih.gov/pubmed/16619224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.20131
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