Phosphorylation of Adf/Cofilin Abolishes Egf-Induced Actin Nucleation at the Leading Edge and Subsequent Lamellipod Extension

In metastatic rat mammary adenocarcinoma cells, cell motility can be induced by epidermal growth factor. One of the early events in this process is the massive generation of actin barbed ends, which elongate to form filaments immediately adjacent to the plasma membrane at the tip of the leading edge...

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Main Authors: Zebda, Noureddine, Bernard, Ora, Bailly, Maryse, Welti, Susan, Lawrence, David S., Condeelis, John S.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2000
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Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174362/
https://ncbi.nlm.nih.gov/pubmed/11086013
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