EGF-induced PIP(2) hydrolysis releases and activates cofilin locally in carcinoma cells

Lamellipodial protrusion and directional migration of carcinoma cells towards chemoattractants, such as epidermal growth factor (EGF), depend upon the spatial and temporal regulation of actin cytoskeleton by actin-binding proteins (ABPs). It is generally hypothesized that the activity of many ABPs a...

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Detalhes bibliográficos
Main Authors: van Rheenen, Jacco, Song, Xiaoyan, van Roosmalen, Wies, Cammer, Michael, Chen, Xiaoming, DesMarais, Vera, Yip, Shu-Chin, Backer, Jonathan M., Eddy, Robert J., Condeelis, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2140025/
https://ncbi.nlm.nih.gov/pubmed/18086920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200706206
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