Internalization, Intracellular Trafficking, and Biodistribution of Monoclonal Antibody 806: A Novel Anti-Epidermal Growth Factor Receptor Antibody

Overexpression of the epidermal growth factor receptor (EGFR) in epithelial tumors is associated with poor prognosis and is the target for a number of cancer therapeutics. Monoclonal antibody (mAb) 806 is a novel anti-EGFR antibody with significant therapeutic efficacy in tumor models when used as a...

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Autores principales: Perera, Rushika M, Zoncu, Roberto, Johns, Terrance G, Pypaert, Marc, Lee, Fook-Thean, Mellman, Ira, Old, Lloyd J, Toomre, Derek K, Scott, Andrew M
Formato: Artigo
Lenguaje:Inglês
Publicado: Neoplasia Press Inc. 2007
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2134906/
https://ncbi.nlm.nih.gov/pubmed/18084617
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