A monoclonal antibody recognizing human cancers with amplification/overexpression of the human epidermal growth factor receptor

Epidermal growth factor receptor (EGFR) has attracted considerable attention as a target for cancer therapy. Wild-type (wt)EGFR is amplified/overexpressed in a number of tumor types, and several mutant forms of the coding gene have been found, with ΔEGFR, a deletion mutation lacking exons 2–7 of the...

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Detalhes bibliográficos
Main Authors: Jungbluth, Achim A., Stockert, Elisabeth, Huang, H. J. Su, Collins, Vincent P., Coplan, Keren, Iversen, Kristin, Kolb, Denise, Johns, Terrance J., Scott, Andrew M., Gullick, William J., Ritter, Gerd, Cohen, Leonard, Scanlan, Matthew J., Cavanee, Webster K., Old, Lloyd J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC141049/
https://ncbi.nlm.nih.gov/pubmed/12515857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.232686499
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