An immunodominant SSX-2–derived epitope recognized by CD4(+) T cells in association with HLA-DR

Ectopic gene expression in tumors versus normal somatic tissues provides opportunities for the specific immunotargeting of cancer cells. SSX gene products are expressed in tumors of different histological types and can be recognized by tumor-reactive CTLs from cancer patients. Here, we report the id...

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Main Authors: Ayyoub, Maha, Hesdorffer, Charles S., Montes, Monica, Merlo, Andrea, Speiser, Daniel, Rimoldi, Donata, Cerottini, Jean-Charles, Ritter, Gerd, Scanlan, Matthew, Old, Lloyd J., Valmori, Danila
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC385406/
https://ncbi.nlm.nih.gov/pubmed/15085202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200420667
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