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A peripheral circulating compartment of natural naive CD4(+) Tregs

CD4(+)CD25(+) Tregs play a central role in the maintenance of peripheral self tolerance by keeping autoreactive T cells in check. Whereas the thymic origin of CD4(+)CD25(+) Tregs, as a distinct lineage, has been inferred, understanding of their developmental pathways has remained elusive. In both mi...

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Autori principali: Valmori, Danila, Merlo, Andrea, Souleimanian, Naira E., Hesdorffer, Charles S., Ayyoub, Maha
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1159133/
https://ncbi.nlm.nih.gov/pubmed/16007258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI23963
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