NY-ESO-1-Specific Circulating CD4(+) T Cells in Ovarian Cancer Patients Are Prevalently T(H)1 Type Cells Undetectable in the CD25(+)FOXP3(+)Treg Compartment

Spontaneous CD4(+) T-cell responses to the tumor-specific antigen NY-ESO-1 (ESO) are frequently found in patients with epithelial ovarian cancer (EOC). If these responses are of effector or/and Treg type, however, has remained unclear. Here, we have used functional approaches together with recently...

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Detalhes bibliográficos
Main Authors: Redjimi, Nassima, Duperrier-Amouriaux, Karine, Raimbaud, Isabelle, Luescher, Immanuel, Dojcinovic, Danijel, Classe, Jean-Marc, Berton-Rigaud, Dominique, Frenel, Jean-Sébastien, Bourbouloux, Emmanuelle, Valmori, Danila, Ayyoub, Maha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3146491/
https://ncbi.nlm.nih.gov/pubmed/21829534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022845
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