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CD4(+) T helper cell responses to NY-ESO-1 tumor antigen in ovarian cancer resist perversion into immunosuppressive Tregs

In a recent study, we have demonstrated that T helper type 1 (T(H)1) cells specific for the tumor antigen NY-ESO-1 are amplified at ovarian tumor sites but are not “perverted” into immunosuppressive FOXP3(+) regulatory T cells (Tregs). These findings encourage the development of protocols aiming to...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Valmori, Danila, Ayyoub, Maha
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4635782/
https://ncbi.nlm.nih.gov/pubmed/26587312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.946370
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