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Monitoring of NY-ESO-1 specific CD4(+) T cells using molecularly defined MHC class II/His-tag-peptide tetramers

MHC-peptide tetramers have become essential tools for T-cell analysis, but few MHC class II tetramers incorporating peptides from human tumor and self-antigens have been developed. Among limiting factors are the high polymorphism of class II molecules and the low binding capacity of the peptides. He...

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Detalhes bibliográficos
Main Authors: Ayyoub, Maha, Dojcinovic, Danijel, Pignon, Pascale, Raimbaud, Isabelle, Schmidt, Julien, Luescher, Immanuel, Valmori, Danila
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2867704/
https://ncbi.nlm.nih.gov/pubmed/20368442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001322107
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