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mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity

A cellular assay has been developed to allow measurement of the inhibitory activity of large numbers of oligonucleotides at the protein level. The assay is centred on an mRNA fusion transcript construct comprising of a full-length reporter gene with a target region of interest inserted into the 3′-u...

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Bibliografiska uppgifter
Huvudupphovsmän: Hüsken, Dieter, Asselbergs, Fred, Kinzel, Bernd, Natt, Francois, Weiler, Jan, Martin, Pierre, Häner, Robert, Hall, Jonathan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2003
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC212822/
https://ncbi.nlm.nih.gov/pubmed/12930976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng103
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