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mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity

A cellular assay has been developed to allow measurement of the inhibitory activity of large numbers of oligonucleotides at the protein level. The assay is centred on an mRNA fusion transcript construct comprising of a full-length reporter gene with a target region of interest inserted into the 3′-u...

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Dettagli Bibliografici
Autori principali: Hüsken, Dieter, Asselbergs, Fred, Kinzel, Bernd, Natt, Francois, Weiler, Jan, Martin, Pierre, Häner, Robert, Hall, Jonathan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC212822/
https://ncbi.nlm.nih.gov/pubmed/12930976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gng103
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