mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity

A cellular assay has been developed to allow measurement of the inhibitory activity of large numbers of oligonucleotides at the protein level. The assay is centred on an mRNA fusion transcript construct comprising of a full-length reporter gene with a target region of interest inserted into the 3′-u...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Hüsken, Dieter, Asselbergs, Fred, Kinzel, Bernd, Natt, Francois, Weiler, Jan, Martin, Pierre, Häner, Robert, Hall, Jonathan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2003
Assuntos:	NAR Methods Online
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212822/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12930976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng103
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