mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity

A cellular assay has been developed to allow measurement of the inhibitory activity of large numbers of oligonucleotides at the protein level. The assay is centred on an mRNA fusion transcript construct comprising of a full-length reporter gene with a target region of interest inserted into the 3′-u...

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Podrobná bibliografie

Vydáno v:	Nucleic Acids Res
Hlavní autoři:	Hüsken, Dieter, Asselbergs, Fred, Kinzel, Bernd, Natt, Francois, Weiler, Jan, Martin, Pierre, Häner, Robert, Hall, Jonathan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Oxford University Press 2003
Témata:	NAR Methods Online
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212822/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12930976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng103
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