mRNA fusion constructs serve in a general cell-based assay to profile oligonucleotide activity

A cellular assay has been developed to allow measurement of the inhibitory activity of large numbers of oligonucleotides at the protein level. The assay is centred on an mRNA fusion transcript construct comprising of a full-length reporter gene with a target region of interest inserted into the 3′-u...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Nucleic Acids Res
Prif Awduron:	Hüsken, Dieter, Asselbergs, Fred, Kinzel, Bernd, Natt, Francois, Weiler, Jan, Martin, Pierre, Häner, Robert, Hall, Jonathan
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Oxford University Press 2003
Pynciau:	NAR Methods Online
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212822/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12930976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gng103
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