Transgenic A(1 )adenosine receptor overexpression increases myocardial resistance to ischemia

Activation of myocardial A(1) adenosine receptors (A(1)AR) protects the heart from ischemic injury. In this study transgenic mice were created using the cardiac-specific α-myosin heavy chain promoter and rat A(1)AR cDNA. Heart membranes from two transgene positive lines displayed ≈1,000-fold overexp...

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Main Authors: Matherne, G. Paul, Linden, Joel, Byford, Anne M., Gauthier, Naomi S., Headrick, John P.
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1997
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC21086/
https://ncbi.nlm.nih.gov/pubmed/9177254
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