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Neuroglobin-overexpressing transgenic mice are resistant to cerebral and myocardial ischemia

Neuroglobin (Ngb), a protein related to myoglobin and hemoglobin but expressed predominantly in the brain, is induced by neuronal hypoxia and cerebral ischemia and protects against hypoxic or ischemic neuronal injury. We engineered transgenic mice that overexpress murine Ngb under the control of a c...

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Detalhes bibliográficos
Main Authors: Khan, Adil A., Wang, Yaoming, Sun, Yunjuan, Mao, Xiao Ou, Xie, Lin, Miles, Erin, Graboski, Justin, Chen, Sylvia, Ellerby, Lisa M., Jin, Kunlin, Greenberg, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693852/
https://ncbi.nlm.nih.gov/pubmed/17098866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607497103
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