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Neuroglobin-overexpressing transgenic mice are resistant to cerebral and myocardial ischemia

Neuroglobin (Ngb), a protein related to myoglobin and hemoglobin but expressed predominantly in the brain, is induced by neuronal hypoxia and cerebral ischemia and protects against hypoxic or ischemic neuronal injury. We engineered transgenic mice that overexpress murine Ngb under the control of a c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Khan, Adil A., Wang, Yaoming, Sun, Yunjuan, Mao, Xiao Ou, Xie, Lin, Miles, Erin, Graboski, Justin, Chen, Sylvia, Ellerby, Lisa M., Jin, Kunlin, Greenberg, David A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1693852/
https://ncbi.nlm.nih.gov/pubmed/17098866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607497103
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