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Neuroglobin attenuates β-amyloid neurotoxicity in vitro and transgenic Alzheimer phenotype in vivo

Neuroglobin (Ngb), a vertebrate globin expressed primarily in neurons, is induced by and protects against neuronal hypoxia and cerebral ischemia. To investigate the spectrum and mechanism of Ngb's neuroprotective action, we studied the effect of transgenic overexpression of Ngb on NMDA and β-am...

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Detalhes bibliográficos
Main Authors: Khan, Adil A., Mao, Xiao Ou, Banwait, Surita, Jin, Kunlin, Greenberg, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141917/
https://ncbi.nlm.nih.gov/pubmed/18025470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706167104
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