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Ischaemic tolerance in aged mouse myocardium: the role of adenosine and effects of A(1) adenosine receptor overexpression

The genesis of the ischaemia intolerant phenotype in aged myocardium is poorly understood. We tested the hypothesis that impaired adenosine-mediated protection contributes to ischaemic intolerance, and examined whether this is countered by A(1) adenosine receptor (A(1)AR) overexpression. Responses t...

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Detalhes bibliográficos
Main Authors: Headrick, John P, Willems, Laura, Ashton, Kevin J, Holmgren, Kirsten, Peart, Jason, Matherne, G Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2342972/
https://ncbi.nlm.nih.gov/pubmed/12717009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2003.041541
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