Chronic β(1)-Adrenoceptor Blockade Impairs Ischaemic Tolerance and Preconditioning in Murine Myocardium

β-adrenoceptor antagonists are commonly used in ischaemic heart disease (IHD) patients, yet may impair signalling and efficacy of ‘cardioprotective’ interventions. We assessed effects of chronic β(1)-adrenoceptor antagonism on myocardial resistance to ischemia-reperfusion (IR) injury and the ability...

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Publicat a:Eur J Pharmacol
Autors principals: Hoe, Louise See, Schilling, Jan M, Busija, Anna R, Haushalter, Kristofer J., Ozberk, Victoria, Keshwani, Malik M., Roth, David M., Toit, Eugene Du, Headrick, John P., Patel, Hemal H., Peart, Jason N.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037019/
https://ncbi.nlm.nih.gov/pubmed/27373851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.06.054
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