Chronic β(1)-Adrenoceptor Blockade Impairs Ischaemic Tolerance and Preconditioning in Murine Myocardium

β-adrenoceptor antagonists are commonly used in ischaemic heart disease (IHD) patients, yet may impair signalling and efficacy of ‘cardioprotective’ interventions. We assessed effects of chronic β(1)-adrenoceptor antagonism on myocardial resistance to ischemia-reperfusion (IR) injury and the ability...

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Bibliografiske detaljer
Udgivet i:Eur J Pharmacol
Main Authors: Hoe, Louise See, Schilling, Jan M, Busija, Anna R, Haushalter, Kristofer J., Ozberk, Victoria, Keshwani, Malik M., Roth, David M., Toit, Eugene Du, Headrick, John P., Patel, Hemal H., Peart, Jason N.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037019/
https://ncbi.nlm.nih.gov/pubmed/27373851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2016.06.054
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